Literature

The Book Mass Spectrometry in Food Safety gives a good overview about up-to-date analytical methods in food safety including a chapter about automated SPE.

Abstract

In the SPE chapter an overview is given of the main potential benefits of using automated SPE in the sample preparation of food samples for LC/MS analysis in terms of quality of analytical results and in terms of productivity and performance.
Automated SPE instrumentation is described and a range of application examples given. The foods used in these applications cover the whole range of sample complexity. In most previous applications, SPE was mainly used for sample clean-up prior to analysis. In this chapter examples are given here in which automated SPE is combined with analyte concentration, analyte derivatization or addition of liquids such as internal standards to further improve limits of quantitation, selectivity, stability and quality of the analysis.

Mass Spectrometry in Food Safety

Methods and Protocols

Series: Methods in Molecular Biology, Vol. 747

Zweigenbaum, Jerry (Ed.)

1st Edition., 2011, XII, 416 p. 104 illus.
Humana Press